Space and Time, or SpaceTime, refers to both to our our perceptions of space and time, and to the mathematical models that combine three dimensions of space and one dimension of time into a four-dimensional manifold.
It is critical to understand that our perceived SpaceTime, and the associated mathematical models, are not fundamental, and that additional dimensions exist.
One can intuitively think of SpaceTime as a simplified user interface that we use to interact with the fundamental underlying Reality.
At the Meta level of analysis, it is critically important that we are striving to actually interact with underlying Reality, and not only our simplified spacial and temporal representation of it.
Our Meta Model will necessarily have to start with the One Thing, advance to the Reality emerging from it, and then map Reality into SpaceTime where we can make predictions and test it.
This is a critical step towards liberating ourselves from the perceived limitations of SpaceTime.